A decaying palazzo on a hilltop near the Adriatic coast, and in the basement, cobwebbed and dusty, an archive unknown to scholars. Here, a young graduate student from Rome makes a discovery that inspires a search for a painting lost for almost two centuries. The artist was Caravaggio, a revolutionary painter beset by personal demons.

Four hundred years ago, he drank and brawled in the taverns and streets of Rome, in and out of jail, all the while painting transcendent works. He rose from obscurity to fame and wealth, but success didn't alter his violent temperament. He died young, alone, and under strange circumstances.

Caravaggio scholars estimate that between sixty and eighty of his works are in existence today. Many others--no one knows the precise number--have been lost to time. Somewhere, surely, a masterpiece lies forgotten.