The Women of Brewster Place depicts seven courageous black women struggling to survive life's harsh realities. Each woman has an individual story to tell. Their stories include the trials and tribulations they endured to end up at Brewster Place; Brewster Place is a dead end street that is cut off from the rest of the town.

The seven women include: Mattie Michael, Etta Mae Johnson, Kiswana Browne, Lucielia Louise Turner, Cora Lee, and Lorraine and Theresa,.